Saint Onisan is a very funny popular manga in Japan, though I am not sure it will be in published in western countries (especially in the U.S). It's a story about Jesus Christ and Buddha. Wiki has only a Japanese page, here is the web translation. Some English blogs wrote about it, here and here are good.
I translated wiki some.
Jesus and Buddha came to the earth from heaven for their vacation. They live at a cheap apartment in Tachikawa, Tokyo and speak Japanese like natives. Jesus wears a crown of thorns (angels put a GPS inside the crown to know where he is always). When he feels stress, he bleeds from stigmata on his forehead and when he is so happy, also when he is super sad, he can makes miracles. But he can't control it by himself, it causes some troubles. He likes to wear underwear after keeping it in the refrigerator. He can't swim at all, he can't even open his eyes in the water. It was a very tough time when he was baptized by John in the Jordan river. Since he has a beard and long hair, he looks like Johnny Depp, and when he picks up chicks, he speaks English. He has the habit of wasting money, he sometimes buys uniforms of SHINSENGUMI (he is a fan of SHINSENGUMI) and gets scorched by Buddha. He writes a blog and finally got number one in a blog ranking. His symbol is not a cross anymore and he thinks it will be a note PC. When he went to Akiba for the first time, he prayed with tears. He likes virtua fighter very much, though he is too bad and has never won before. When he went to a public sauna, he saw a Yakuza who had a tattoo of some god of Buddhism. He misunderstand the Yakuza was a devotional Buddhist and talked to him, but accidentally they could be good friends. Now he earns some respect from lower Yakuza. He really likes Japanese style stand up comedy 'Manzai'(Takeshi Kitano did it), and he made a duo with Buddha. The name of the duo is 'Punch and long hair'.
The Buddha came to Japan because Jesus asked him to go. He can speak Japanese as a native too. Like we say 'Even Buddha may be upset if his face is hit three times', when someone makes him angry three times, he will get a terrible thing. In such cases, he becomes luminous. He has long long ear lobes and short rolled hair (this type of perm is called 'punch' in Japan, Yankee or Yakuza love that hair style). His cell phone is Docomo and his Nintendo DS is a gross silver color, it was a present from Jesus. He washes his hair in Asience and he likes cleaning, washing and cooking. He is a vegetarian but he cooks some meat for Jesus's lunch box. When he takes a shower a long time, he almost reaches to the truth of the cosmos. He is very good at swimming and he is called 'the rumble fish of the Ganges'. He is a specialist at fasting, he can fast until he becomes bone and skin only. He is a very economical person and cautions Jesus about wasting money. But when he read 'Buddha' of Osamu Tezuka in a manga cafe, he was blown away with tears and got serious for once. After that, Buddha respects Tezuka like a religion and he started to draw manga too. Jesus read his manga and made a miracle because he laughed so much. But the manga is a joke of heaven, nobody can't understand it usually. He can get microwaves from Terrestrial Digital Broadcasting, and they watch TV with his power. His hobby is making silk screens, 30% of their T-shorts are his handmade, they are simple but sometime so bad joke.
Do you think 'Saint Young Men' can be published? I guess some will say the manga is disrespectful. :-)